IDO1/TDO-IN-10 (Compound G-14) is a dual IDO1 (EC50=3.07 µM) and TDO (EC50=9.7 µM) inhibitor. IDO1/TDO-IN-10 inhibits the conversion of tryptophan to kynurenine and modulates immune responses while reducing inflammatory reactions. IDO1/TDO-IN-10 is promising for research of cancers and inflammatory diseases[1].
Molecular Weight:
436.57
Formula:
C24H28N4O2S
Target:
Indoleamine 2,3-Dioxygenase (IDO)
Application Notes:
MCE Product type: Reference compound1
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