WRN inhibitor 20 (Compound 14c) is a WRN degradation agent. WRN inhibitor 20 exhibits strong degradation activity in various cells, such as HCT-116 (DC50 = 1.7 µM), SW-48 (DC50 = 3.0 µM), and SW-480 (DC50 = 5.9 µM) cells. WRN inhibitor 20 exhibits potent anti proliferative, pro apoptotic, migration inhibiting, and DNA damage inducing effects in MSI-H cells. WRN inhibitor 20 can be used for research on cancer[1].
Molecular Weight:
727.84
CAS Number:
[3095277-20-3]
Formula:
C37H44F3N5O5S
Target:
Apoptosis,DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound1
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