SDH-IN-36 (Compound 17) is a derivative of alpha-D-tocopherol. SDH-IN-36 increases ROS and induces apoptosis by inhibiting SDHC and blocking electron transfer. SDH-IN-36 can inhibit the proliferation of various tumor cells, such as SSK4 (GI50 = 0.156 µM), SSNU638 (GI50 = 0.659 µM), and SKATOIII (GI50 = 0.490 µM) cells. SDH-IN-36 can significantly inhibit tumor growth. SDH-IN-36 can be used for research on cancers such as gastric cancer[1].
Molecular Weight:
487.76
CAS Number:
[261929-60-6]
Formula:
C31H53NO3
Target:
Apoptosis,Mitochondrial Metabolism,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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