BAS00602705 is an E-cadherin inhibitor. BAS00602705 exerts its function by blocking the trans-interactions of E-cadherin molecules within junctional complexes, without permanently altering E-cadherin expression levels. BAS00602705 significantly impairs invadopodia formation in pancreatic cancer cells. BAS00602705 can be used for the study of anti-invasive therapeutic strategies in cancers characterized by dysregulated E-cadherin-mediated invadopodia activity, such as pancreatic ductal adenocarcinoma (PDAC)[1].
Molecular Weight:
492.36
Purity:
98.96
CAS Number:
[317321-89-4]
Formula:
C25H22BrN3O3
Target:
Cadherin
Application Notes:
MCE Product type: Reference compound
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