JNK-IN-25 is a potent and selective JNK1/2/3 inhibitor with IC50 values of 1.54 (JNK1), 1.99 (JNK2), and 0.75 nM (JNK3), respectively. JNK-IN-25 inhibits phosphorylation of c-Jun in cells via covalently bonding with the conserved cysteine of JNK1/2/3. JNK-IN-25 can be used for research of cancer, inflammatory and neurodegenerative diseases[1].
Molecular Weight:
493.56
CAS Number:
[1644498-54-3]
Formula:
C28H27N7O2
Target:
JNK
Application Notes:
MCE Product type: Reference compound
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