DC-PRC2in-01, CAS [[120430-77-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178694
Supplier Catalog Number:
HY-178694
Alternative Catalog Number:
MCE-HY-178694-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
DC-PRC2in-01 is a potent EZH2-EED interaction inhibitor with an IC50 of 4.21 µM and a Kd of 4.56 µM. DC-PRC2in-01 disrupts the EZH2-EED interaction, leading to degradation of PRC2 core proteins and decrease of H3K27me3 levels, inhibition of PRC2-driven lymphoma cell proliferation, and cell cycle arrest. DC-PRC2in-01 can be used for the research of PRC2-related cancers, such as Diffuse Large B-cell Lymphoma (DLBCL) and follicular lymphoma (FL)[1].
Molecular Weight:
444.54
CAS Number:
[120430-77-5]
Formula:
C27H29FN4O
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Oligonucleotides
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