CT 32228 is an inhibitor of lysophosphatidic acid acyltransferase-beta (LPAAT-beta). CT 32228 inhibits tumor cell growth. CT 32228 exhibits IC50 values of around 0.1-0.8 µM in various leukemia cell lines. CT 32228 induces caspase activation in DHL-4 and Ramos cells. CT 32228 induces apoptosis when combined with Rituximab (HY-P9913). CT 32228 results in a 50% xenograft growth delay in vivo. CT 32228 can be studied in research on acute leukemia[1][2].
Molecular Weight:
390.66
CAS Number:
[521064-34-6]
Formula:
C16H13BrClN5
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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