NM-002 is a metabolite of prodrug NM-001 (HY-178819), with NIR emission. NM-002 generates through activates the prodrug NM-001 by overexpressed Cathepsin B (CTSB) within tumor cells. NM-002 has no toxicity towards tumor cells and can escape from the lysosomes into the cytoplasm. NM-002 can be used for real-time drug release monitoring research[1].
Molecular Weight:
1349.88
Formula:
C65H81ClN14O16
Target:
Drug Metabolite
Application Notes:
MCE Product type: Reference compound
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