Y502-2304 is a c-Myc G-quadruplex stabilizer. Y502-2304 exhibits potent antiproliferative activity in multiple myeloma (MM) cells. Y502-2304 downregulates c-Myc mRNA and protein expression. Y502-2304 induces apoptosis in MM cells, characterizes by elevated gammaH2AX levels, increases reactive oxygen species (ROS) generation, and mitochondrial dysfunction. Y502-2304 significantly inhibits tumor growth in a xenograft MM model. Y502-2304 can be used for the study of multiple myeloma[1].
Molecular Weight:
369.35
CAS Number:
[741278-95-5]
Formula:
C16H11N5O4S
Target:
Apoptosis,c-Myc,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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