Mcl-1-IN-20 (Compound 26d) is a Mcl-1 inhibitor with Kis of 0.59, 6.6 and 3.6 µM against Mcl-1, Bcl-xL and Bcl-2. Mcl-1-IN-20 exhibits significant anti-proliferative activity against pancreatic cancer cells and can induce apoptosis in BxPC-3 cells. Mcl-1-IN-20 can be used for the study of pancreatic cancer[1].
Molecular Weight:
701.21
Formula:
C35H29ClN4O6S2
Target:
Apoptosis,Bcl-2 Family
Application Notes:
MCE Product type: Reference compound
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