N-19004 is a FPR1 antagonist. N-19004 shows broad-spectrum antibacterial effects against a variety of pathogens. N-19004 exhibits significant retinal protective effects in the rd10 mouse model of retinitis pigmentosa (RP). N-19004 can attenuate retinal dysfunction, mitigate rod and cone degeneration, and reduce immune cell activation, gliosis, inflammation, oxidative stress, and apoptosis. N-19004 can reduce the size of laser-induced choroidal lesions and promote edema absorption through dual anti-inflammatory and anti-angiogenic effects. N-19004 can be used for the research of retinal degenerative diseases such as retinitis pigmentosa[1][2].
Molecular Weight:
562.73
CAS Number:
[2996841-28-0]
Formula:
C29H38N8O2S
Target:
Apoptosis,Bacterial,Formyl Peptide Receptor (FPR)
Application Notes:
MCE Product type: Reference compound
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