HJ-4 is a Piperine (HY-N0144) derivative. HJ-4 potently inhibits the proliferation of CRC cells by dose-dependently reducing colony formation and DNA synthesis. HJ-4 markedly suppresses the adhesion, migration, invasion and induces apoptosis of CRC cells. HJ-4 demonstrates anti-tumor efficacy in chicken embryo chorioallantoic membrane (CAM) model implanted with HCT116/SW480 tumor spheroids. HJ-4 can be used for the study of colorectal cancer (CRC)[1].
Molecular Weight:
392.45
Purity:
98.02
CAS Number:
[1313741-00-2]
Formula:
C23H24N2O4
Target:
Apoptosis,Drug Derivative
Application Notes:
MCE Product type: Reference compound
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