Antitumor agent-207 is a Pt(IV)-NO prodrug with high lipid solubility, good stability, and excellent tumor targeted release ability. Antitumor agent-207 has significant anti proliferative activity in various cells such as TE-1 (IC50 = 1.79 µM), TE-10 (IC50 = 1.95 µM), KYSE-30 IC50 = 5.99 µM), KYSE-520 (IC50 = 5.53 µM) cells. Antitumor agent-207 can significantly enhance intracellular Pt accumulation and DNA platformization levels, and effectively release NO. Antitumor agent-207 can be used for research on cancers such as esophageal cancer[1].
Molecular Weight:
877.56
Formula:
C26H32Cl2F3N7O7Pt
Target:
Drug Metabolite
Application Notes:
MCE Product type: Reference compound
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