SLK/STK10-IN-2 (Compound 23) is a highly selective STK10 inhibitor, with a Kd of 365 nM and an IC50 of 0.85 µM. SLK/STK10-IN-2 exhibits EC50 of 0.89 µM in NanoBRET cell experiments. SLK/STK10-IN-2 shows no significant binding to SLK, STK3/4. SLK/STK10-IN-2 can be used to study STK10-related diseases (such as abnormal lymphocyte migration)[1].
Molecular Weight:
492.96
Formula:
C25H25ClN6O3
Target:
Ser/Thr Kinase
Application Notes:
MCE Product type: Reference compound
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