Apelin agonist 2 (Compound 35) is an orally active APLNR agonist. Apelin agonist 2 can significantly inhibit the accumulation of cAMP (EC50 = 10 nM). Apelin agonist 2 exhibits a significant improvement in glucose tolerance. Apelin agonist 2 can be used to study metabolic diseases such as diabetes[1].
Molecular Weight:
499.82
Formula:
C20H15ClF5N7O
Target:
Apelin Receptor (APJ)
Application Notes:
MCE Product type: Reference compound
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