SHP2-IN-45, CAS [[2949435-53-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178983
Supplier Catalog Number:
HY-178983
Alternative Catalog Number:
MCE-HY-178983-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
SHP2-IN-45 (Compound 6) is a potent, highly selective, and orally active SHP2 allosteric inhibitor. SHP2-IN-45 significantly reduces the expressions of IL-6, TNF-alpha, IL-1beta, and iNOS. SHP2-IN-45 inhibits the polarization of M1-type macrophages. SHP2-IN-45 can inhibit the NF-kappaB pathway. SHP2-IN-45 can be used in the research of sepsis and acute lung injury[1].
