PI3Kalpha-IN-28, CAS [[3095278-75-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-178984
Supplier Catalog Number:
HY-178984
Alternative Catalog Number:
MCE-HY-178984-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PI3Kalpha-IN-28 (Compound 23) is an efficient dual targeted PI3K/BRD4 inhibitor. PI3Kalpha-IN-28 can inhibit the proliferation of various cells, such as KYSE180 and KYSE450 cells. PI3Kalpha-IN-28 can concentration dependently inhibit migration and colony formation, induce G0/G1 phase arrest, significantly inhibit DNA synthesis, and significantly increase the proportion of senescent cells. PI3Kalpha-IN-28 can inhibit the expression of p-AKT and c-Myc and activate the AMPK-p27 pathway. PI3Kalpha-IN-28 can be used for research on cancers such as esophageal cancer[1].
