BJH-86 is a soluble mitochondrial complex 1 inhibitor (oxygen consumption rate inhibition IC50 = 5 µM). BJH-86 exhibits weak inhibitory activity against phosphodiesterase 10A (PDE10A) (IC50 >10 µM). BJH-86 can reduce cellular oxygen consumption and inhibit cancer cell proliferation. BJH-86 can be used for the research of cancer, such as lung cancer[1].
Molecular Weight:
371.43
CAS Number:
[3067849-10-6]
Formula:
C23H21N3O2
Target:
Mitochondrial Metabolism,Phosphodiesterase (PDE)
Application Notes:
MCE Product type: Reference compound
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