Antibacterial agent 299 (Compound P5) is a highly effective antibacterial agent against Xanthomonas oryzae pv. oryzae (Xoo), with an EC50 value of 6.9 µg/mL. Antibacterial agent 299 integrates into bacterial membranes, disrupts membrane structure, inhibits biofilm formation, and thus exerts antibacterial effects. Antibacterial agent 299 also shows inhibitory activity against Xanthomonas oryzae pv. oryzicola (Xoc) (EC50 = 32.5 3.0 µg/mL), but its activity against Xanthomonas axonopodis pv. citri (Xac) is weaker. Antibacterial agent 299 demonstrated excellent control efficacy in a rice bacterial blight (BLB) model. Antibacterial agent 299 can be used for BLB research[1].
Molecular Weight:
450.45
Formula:
C23H25F3N2O4
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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