CYP3A4-IN-6 (Compound 8a) is a CYP3A4 inhibitor with tissue-selective metabolism. CYP3A4-IN-6 remains stable in the intestinal S9 component but is rapidly metabolized in the liver S9 component, forming a less active metabolite. CYP3A4-IN-6 can be used for intestinal selectivity studies[1].
Molecular Weight:
322.36
Formula:
C19H18N2O3
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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