Psa-AR is a PROTAC degrader targeting PSMA, with a Kd of 7.2 nM. Psa-AR exhibits strong degradation capabilities for AR, AR-V7, and HSP90, and induces cell apoptosis. Psa-AR demonstrates potent tumor suppressive activity in the 22Rv1 xenograft tumor model. Psa-AR can be used in the research of castration-resistant prostate cancer[1].
Molecular Weight:
2354.38
Formula:
C110H120F4N22O29S2
Target:
Androgen Receptor,Apoptosis,HSP,PROTACs,PSMA
Application Notes:
MCE Product type: Reference compound
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