JOSD2-IN-1 (Compound 31) is a covalent JOSD2 inhibitor with an IC50 value of 1.95 µM. JOSD2-IN-1 inhibits JOSD2, thereby down-regulating KRAS expression. JOSD2-IN-1 exhibits significant anti-proliferative activity against HCT116 cells. JOSD2-IN-1 can be used for research on colorectal cancer[1].
Molecular Weight:
472.58
Formula:
C27H32N6O2
Target:
Deubiquitinase,Ras
Application Notes:
MCE Product type: Reference compound
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