EIF2B-IN-1 (Compound A) is an eIF2B inhibitor. EIF2B-IN-1 binds eIF2B. EIF2B-IN-1 stabilises the eIF2B decamer and favours inhibitory eIF2B:eIF2(alphaP) complex formation. EIF2B-IN-1 exhibits weak displacement of ISRIB. EIF2B-IN-1 can be used in the research of integrated stress responses[1].
Molecular Weight:
563.63
Formula:
C30H37F4N3O3
Target:
Eukaryotic Initiation Factor (eIF)
Application Notes:
MCE Product type: Reference compound
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