PROTAC IKKbeta/NR4A1 degrader-1, CAS [[2826215-20-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179112
Supplier Catalog Number:
HY-179112
Alternative Catalog Number:
MCE-HY-179112-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PROTAC IKKbeta/NR4A1 degrader-1 is a highly efficient and effective dual-PROTAC degrader targeting IKKbeta and NR4A1. PROTAC IKKbeta/NR4A1 degrader-1 can increase the levels of caspase 3 and cleaved caspase 3 proteins, while the necroptosis marker RIP kinase remained unchanged, indicating that it can induce apoptosis. PROTAC IKKbeta/NR4A1 degrader-1 can be used for the study of Acute myeloid leukemia (AML). Red: IKKbeta/NR4A1 ligand (HY-13067), Blue: E3 ligase CRBN ligand (HY-14658), Black: Linker (HY-79577)[1].
