BL-1005 (BS2463), thiophen-2-yl pyrimidine (TTP), is a potent paralytic of Schistosoma mansoni with an EC50 of 37 nM. BL-1005 shows low cytotoxicity for HEK293, HeLa and HepG2 cell with CC50 >20 µM. BL-1005 can induce paralysis in both adult and juvenile S. mansoni. BL-1005 can be used for the research of infection[1].
Molecular Weight:
422.88
Formula:
C19H17ClF2N4OS
Target:
Parasite
Application Notes:
MCE Product type: Reference compound
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