AKT-100 is a p53 reactivation agent. AKT-100 significantly inhibits the proliferation of various ovarian and endometrial cancer cells at low concentrations. AKT-100 can upregulate cell cycle regulatory genes (such as p21, GADD45) and pro apoptotic genes (such as NOXA, DR5), and inhibit DNA repair pathways. AKT-100 is commonly used in cancer research[1].
Molecular Weight:
522.62
CAS Number:
[3076960-67-0]
Formula:
C31H32N5O3
Target:
MDM-2/p53
Application Notes:
MCE Product type: Reference compound
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