TN-783 is an orally active, brain-penetrant NLRP3 (IC50 = 19.3 nM) inhibitor. TN-783 enhances the effects of the GLP-1 receptor agonist semaglutide. TN-783 requires sustained targeted action, not permanent metabolic remodeling. TN-783 can be used for the study of obesity[1].
Molecular Weight:
494.18
CAS Number:
[2771021-30-6]
Formula:
C16H11F4IN4O2
Target:
NOD-like Receptor (NLR)
Application Notes:
MCE Product type: Reference compound
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