EGFR-IN-185 is a EGFR inhibitor. EGFR-IN-185 exhibits potent activity against non-small cell lung cancer (NSCLC) cells harboring EGFR mutations. EGFR-IN-185 inhibits colony formation and migration, induces G0/G1 arrest, and promots apoptosis, which are associated with the suppression of EGFR and AKT phosphorylation. EGFR-IN-185 can be used for the research of NSCLC[1].
Molecular Weight:
481.56
Formula:
C30H28FN3O2
Target:
Akt,Apoptosis,EGFR
Application Notes:
MCE Product type: Reference compound
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