EGFR-IN-184 (compound 5p) is an EGFR inhibitor (IC50 = 65.6 nM). EGFR-IN-184 has anti proliferative activity against various tumor cells, such as T47D (IC50 = 15 µM), PC3 (IC50 = 55 µM), HCT116 (IC50 = 36 µM) cells. EGFR-IN-184 can significantly induce cell apoptosis and block the cell cycle. EGFR-IN-184 can be used for research on various types of cancer[1].
Molecular Weight:
441.89
Formula:
C20H16ClN5O3S
Target:
Apoptosis,EGFR
Application Notes:
MCE Product type: Reference compound
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