DEL-C1 is a CHI3L1 inhibitor. DEL-C1 can restore the ability to clear Amyloid-beta and repair lysosomal function of astrocytes. DEL-C1 can inhibit NF-kappaB signaling and IL-6 secretion. DEL-C1 can be used for the researches of inflammation and neurological disease, such as Alzheimers disease[1].