AP-7-168, molecular glues, is a beta-arrestin-biased negative allosteric modulator of the beta2-adrenergic receptor (beta2AR). AP-7-168 can promote beta2AR homodimerization and inhibit GRK5-mediated beta2AR phosphorylation. AP-7-168 can sustain bronchorelaxation in cell and tissue. AP-7-168 can be used for the researches of inflammation and immunology, such as asthma[1].
Molecular Weight:
433.29
CAS Number:
[2816062-15-2]
Formula:
C20H19BrF2N4
Target:
Adrenergic Receptor,Molecular Glues
Application Notes:
MCE Product type: Reference compound1
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