ERalpha antagonist 2 (Compound 5b) is an ER-alpha antagonist with an IC50 value of 1729 nM. ERalpha antagonist 2 exhibits significant inhibitory activity against breast cancer cell lines, and is still effective against ER-negative cells (MDA-MB-231), suggesting the existence of ER-independent pathways. ERalpha antagonist 2 can be used for the study of breast cancer[1].
Molecular Weight:
802.96
Formula:
C46H38N6O4S2
Target:
Estrogen Receptor/ERR
Application Notes:
MCE Product type: Reference compound1
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