LD5097 is a highly effective and selective PROTAC degrader targeting RIPK1. LD5097 can rapidly and efficiently downregulate RIPK1 and significantly enhance TNFalpha-mediated apoptosis in Jurkat cells. LD5097 significantly increases the levels of cleaved caspase-3/7 and PARP. LD5097 can be used for the study of acute T-lymphoblastic leukemia[1].
Molecular Weight:
1382.53
Formula:
C74H75F4N13O8S
Target:
Apoptosis,Caspase,PARP,PROTACs,RIP kinase
Application Notes:
MCE Product type: Reference compound1
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