Wee1/HDAC-IN-1, CAS [[3037071-29-4]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179272
Supplier Catalog Number:
HY-179272
Alternative Catalog Number:
MCE-HY-179272-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Wee1/HDAC-IN-1 is a dual Wee1/HDAC inhibitor with an IC50 of 1.2 nM for Wee1 and IC50 values of 196 nM for HDAC1, 156 nM for HDAC3, and 55 nM for HDAC6. Wee1/HDAC-IN-1 exhibits strong antiproliferative activity against MV4-11 cells with an IC50 of 0.076 µM. Wee1/HDAC-IN-1 selectively binds to Wee1 and HDACs. Wee1/HDAC-IN-1 interferes with DNA damage repair pathways and induces apoptosis in MV4-11 cells. Wee1/HDAC-IN-1 Wee1/HDAC-IN-1 can be used for the research of acute myeloid leukemia (AML)[1].
Molecular Weight:
629.75
CAS Number:
[3037071-29-4]
Formula:
C33H43N9O4
Target:
Apoptosis,HDAC,Wee1
Application Notes:
MCE Product type: Reference compound1
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