KR-27452 is a selective and orally active PI4KIIIbeta inhibitor with an IC50 of 0.026 µM, while showing no activity against PI4KIIIalpha (IC50 >10 µM) . KR-27452 specifically binds to and inhibits PI4KIIIbeta, leading to reduced viral replication in cells. KR-27452 exhibits strong antiviral activity against human rhinovirus (RVs) and Coxsackievirus (COXs). KR-27452 can be used for the research of infection[1].
Molecular Weight:
453.55
Formula:
C24H27N3O4S
Target:
Enterovirus,PI4K
Application Notes:
MCE Product type: Reference compound
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