ACI-19278 is a TDP-43 PET tracer with an average Kd of 25 nM. ACI-19278 only binds to pathological TDP-43 aggregates and does not cross-react with Abeta, Tau, etc. [18F]ACI-19278 successfully visualized the TDP-43 pathology in the human brain through positron emission computed tomography. ACI-19278 can be used for in vivo diagnosis of TDP-43 protein lesions[1].
Molecular Weight:
413.44
CAS Number:
[3033951-64-0]
Formula:
C20H17F2N5OS
Target:
hnRNP
Application Notes:
MCE Product type: Reference compound
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