BSJ-04-146, CAS [[2414478-45-6]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179512
Supplier Catalog Number:
HY-179512
Alternative Catalog Number:
MCE-HY-179512-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
BSJ-04-146 is a highly efficient and selective PROTAC targeting focal adhesion kinase (FAK) inhibitor(IC50 = 26 nM). BSJ-04-146 achieves rapid and potent FAK degradation with high proteome-wide specificity in cancer cells and induces durable degradation in mice. BSJ-04-146 binds FAK and requires the ubiquitin-proteasome machinery to achieve FAK degradation. BSJ-04-146 can be used for the study of pancreatic cancer and triple-negative breast cancer[1].
Molecular Weight:
955.03
CAS Number:
[2414478-45-6]
Formula:
C50H57F3N8O8
Target:
FAK,PROTACs
Application Notes:
MCE Product type: Reference compound
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