Umbelopsisin A is a GABAA and GABAB non-selective agonist. Umbelopsisin A activates the GABAergic pathway, including notch signaling and fatty acid metabolism. Umbelopsisin A shows dual neuroprotection against glutamate excitotoxicity in vitro (reducing ROS and cell death) and in vivo. Umbelopsisin A can be used for the study of glaucoma and broader neurodegenerative disease applications[1].
Molecular Weight:
365.38
Formula:
C21H19NO5
Target:
GABA Receptor,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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