Carba1 is a bifunctional Carbazole (HY-D0204) derivative that activates nicotinamide phosphoribosyltransferase (NAMPT) and enhances NAD biosynthesis. Carba1 binds to colchicine site of tubulin, enhancing the anti-tumor effect of various chemotherapy drugs, such as Paclitaxel (HY-B0015). Carba1 exerts neuroprotective effect and can regulate cell energy metabolism. Carba1 can be used for the researches of cancer and chemotherapy-induced peripheral neuropathy (CIPN)[1].
Molecular Weight:
294.78
Purity:
98.23
CAS Number:
[2635394-10-2]
Formula:
C18H15ClN2
Target:
Drug Derivative,Microtubule/Tubulin,NAMPT
Application Notes:
MCE Product type: Reference compound
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