DL78 is an effective anti-mitotic agent. DL78 induces mitotic arrest, mitotic catastrophe and apoptosis in cancer cells by disrupting the interaction between Myc and alpha-tubulin. DL78 exhibits broad anti-cancer activity, especially against cancer cells with chromosomal instability and excessive expression of MYC. DL78 significantly reduces tumor burden in the OV81.2 xenograft model. DL78 can be used for the study of ovarian cancer[1].
Molecular Weight:
336.34
Purity:
99
CAS Number:
[132993-79-4]
Formula:
C20H16O5
Target:
Apoptosis,c-Myc,Microtubule/Tubulin
Application Notes:
MCE Product type: Reference compound
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