DHODH-IN-33, CAS [[3026839-88-0]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179531
Supplier Catalog Number:
HY-179531
Alternative Catalog Number:
MCE-HY-179531-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
DHODH-IN-33 is a selective dihydroorotate dehydrogenase (DHODH) inhibitor with potent activity against A549 (IC50 = 5.22 µM) and 5637 (IC50 = 3.03 µM). DHODH-IN-33 induces autophagy-dependent ferroptosis (mitochondrial dysfunction, lipid peroxidation, and ROS accumulation) with no notable toxicity in vivo. DHODH-IN-33 exerts anti-cancer effect by promoting the autophagy-dependent degradation of DHODH. DHODH-IN-33 can be used for non-small cell lung cancer and bladder cancer[1].
Molecular Weight:
407.48
CAS Number:
[3026839-88-0]
Formula:
C23H21NO4S
Target:
Autophagy,Ferroptosis,ROS Kinase
Application Notes:
MCE Product type: Reference compound
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