Avanafil metabolite M4, CAS [[2656442-91-8]] Preis auf Anfrage

Product Overview

• Article Name: Avanafil metabolite M4, CAS [[2656442-91-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-179550
• Supplier Catalog Number: HY-179550
• Alternative Catalog Number: MCE-HY-179550-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Avanafil metabolite M4 (Compound M-4ii) is a metabolite of Avanafil (HY-18252). Avanafil is a selective Phosphodiesterase-5 (PDE-5) inhibitor with IC50s of 5.2, 630, 5700, 6200, 12000, 27000, 51000 and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cGMP hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis[1][2][3][4].

Product Properties

• Molecular Weight: 499.95
• CAS Number: [2656442-91-8]
• Formula: C23H26ClN7O4
• Target: Drug Metabolite,Phosphodiesterase (PDE),PKG

Application Notes

• Application Notes: MCE Product type: Reference compound