Cbl-b-IN-29, CAS [[3070411-10-5]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179575
Supplier Catalog Number:
HY-179575
Alternative Catalog Number:
MCE-HY-179575-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Cbl-b-IN-29 is an orally active CBL-B inhibitor. Cbl-b-IN-29 binds to the CBL-B active pocket. Cbl-b-IN-29 induces Jurkat cell release IL-2 with an EC50 of 159 nM, effectively inhibiting the function of immune E3 ubiquitin ligase. Cbl-b-IN-29 demonstrates robust anti-tumor efficacy in vivo with good tolerability and no observed adverse reactions. Cbl-b-IN-29 can be used for cancer immunotherapy, colorectal cancer and immune-oncology combination research[1].
Molecular Weight:
499.62
CAS Number:
[3070411-10-5]
Formula:
C30H34FN5O
Target:
E1/E2/E3 Enzyme,Interleukin Related
Application Notes:
MCE Product type: Reference compound
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