PIN1 degrader-3, CAS [[3101950-55-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179577
Supplier Catalog Number:
HY-179577
Alternative Catalog Number:
MCE-HY-179577-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PIN1 degrader-3 is a Pin1 (peptidyl-prolyl isomerase protein) (IC50 = 4.65 nM) degrader. PIN1 degrader-3 bound covalently to Pin1. PIN1 degrader-3-induced Pin1 degradation reduced cell viability, with EC50 values after 72 h of 8.4 µM in MIA PaCa-2 cells and 5.3 µM in KPC cell lines.PIN1 degrader-3 can destabilize Pin1 in vitro, causing its degradation in cells. PIN1 degrader-3 can be used for the study of pancreatic cancer[1].
Molecular Weight:
625.55
CAS Number:
[3101950-55-1]
Formula:
C31H34Cl2N6O4
Target:
PIN1
Application Notes:
MCE Product type: Reference compound
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