RIPK1-IN-38, CAS [[3092834-30-2]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179680
Supplier Catalog Number:
HY-179680
Alternative Catalog Number:
MCE-HY-179680-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
RIPK1-IN-38 is an orally active RIPK1 inhibitor with an IC50 value of 27 nM. RIPK1-IN-38 can inhibit the phosphorylation of RIPK1 and its downstream signaling molecules RIPK3 and MLKL. RIPK1-IN-38 exhibits anti-necroptotic activity. RIPK1-IN-38 has excellent anti-inflammatory efficacy in both the SIRS model and GVHD model. RIPK1-IN-38 can be used for the research of inflammatory and immune-related diseases[1].