VS3 is a YAP-TEAD interaction inhibitor. VS3 directly disrupts the interaction between YAP-TEAD by binding to TEAD4 Interface 3 (Kd = 6 µM) on the surface. VS3 exhibits anti-proliferative activity against HT29, HCT116, and A2780. VS3 can be used for research on colorectal adenocarcinoma and ovarian cancer[1].
Molecular Weight:
363.41
CAS Number:
[2576427-49-9]
Formula:
C21H21N3O3
Target:
YAP
Application Notes:
MCE Product type: Reference compound
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