GSK3beta-IN-4, CAS [[3083425-61-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-179723
Supplier Catalog Number:
HY-179723
Alternative Catalog Number:
MCE-HY-179723-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
GSK3beta-IN-4 is a selective, potent, orally active and brain-penetrant ATP-competitive GSK3beta inhibitor with an IC50 of 0.37 nM. GSK3beta-IN-4 shows an IC50 of 2.75 nM and SI of 7.4 for GSK3alpha. GSK3beta-IN-4 reduces tau phosphorylation at Ser396 by inhibiting GSK3beta and imoroves cognitive deficits in Alzheimers disease models. GSK3beta-IN-4 can be used for the research of Alzheimers disease[1].
Molecular Weight:
426.51
CAS Number:
[3083425-61-7]
Formula:
C26H26N4O2
Target:
GSK-3,Tau Protein
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted