Antibacterial agent 307 is an antibacterial agent. Antibacterial agent 307 shows MICs of 1-4 µg/mL against Gram-positive bacteria, moderate activity against Gram-negative bacteria, low hemolytic toxicity, and excellent plasma stability. Antibacterial agent 307 compromises bacterial membrane integrity via increased permeability and depolarization, induces endogenous ROS accumulation, causes cytoplasmic protein and nucleic acid leakage, and drives rapid bacterial cell death. Antibacterial agent 307 can be used for the research of bacterial infection[1].
Molecular Weight:
524.38
Formula:
C23H25BrF3N5O
Target:
Bacterial,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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