AF03 is a larvicide against Aedes aegypti Vector Larvae with a LC50 of 41.6 µg/mL. AF03 binds stably to the sterol carrier protein-2 (AeSCP-2) of Aedes aegypti, interfering with lipid metabolism in larvae. AF03 can increase acetylcholinesterase (AChE) activity in the zebrafish brain, slightly elevate catalase (CAT) activity in the liver and heart, and increased superoxide dismutase (SOD) activity in the brain. AF03 can be used for the research of arboviruses infection, such as Dengue[1].
Molecular Weight:
221.68
Formula:
C12H12ClNO
Target:
Cholinesterase (ChE),Insecticide,SOD
Application Notes:
MCE Product type: Reference compound
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