Antibacterial agent 306 (Compound 8c), a lactate dehydrogenase inhibitor, is a highly effective antibacterial agent, especially effective against Gram-positive bacteria. Antibacterial agent 306 exhibits MIC against Staphylococcus aureus of as low as 1 µg/mL. Antibacterial agent 306 can not only damage membrane integrity and block the replication of DNA by intercalation, but also make reactive oxygen species (ROS) burst. Antibacterial agent 306 can be used for research on anti-multi-drug resistant bacteria[1].
Molecular Weight:
498.33
Formula:
C23H20BrN3O5
Target:
Bacterial,DNA/RNA Synthesis,Lactate Dehydrogenase,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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